MOTS-C - 10mg
MOTS-c is a mitochondrial-derived peptide that plays a significant role in metabolic regulation, particularly concerning glucose uptake, lipid metabolism, and insulin resistance, with potential therapeutic applications in diabetes, obesity, and age-related diseases. C-peptide, on the other hand, is a marker of endogenous insulin secretion produced by the beta cells of the pancreas.
MOTS-c:
- Origin and Function: Encoded by the mitochondrial genome (specifically the 12S rRNA region), MOTS-c translocates to the nucleus and regulates nuclear gene expression, influencing metabolic pathways and stress responses. It is activated by stress and exercise but its expression decreases with age.
- Potential Benefits: Research suggests MOTS-c can improve glucose metabolism, enhance physical performance, promote mitochondrial function, reduce obesity and insulin resistance, and even has potential in treating inflammatory disorders and promoting bone growth.